About
I have done my resarch in natural products as potent Anticancer agent. I have been awarded Women Scientist award in the form of three year grant from Department of Science & Technoloy, Government of India for carrying out latest research in the field of cancer.
Qualification
Ph.D.
Experience
2 years as assistent Professor Department of chemistry, Shia PG Collge. Lucknow
Research & Publication
Research paper
1. Fatima, N., Ahmad, M.K., Ansari,
J.A., Ali, Z., Khan, A.R., Mahdi A.A. (2016) Anticancer, antioxidant potential
and profiling of polyphenolic compounds of Wrightia tinctoria Roxb.
(R.Br.) bark. Journal of Advance Pharmaceutical
Technology Research, 7,159-65.
2. Fatima, N., Ahmad, M.K.,
Ansari, J.A., Khan, H.J., Rastogi, N., Srivastava, S.K., Ahmad, S., Ali, Z.
(2016). Antiproliferative and antioxidant studies of Anthocephalus cadamba Rox.
Miq. Bark. Indian Journal of
Pharmaceutical Science, 78(4), 525-531.
3. Ansari, J.A.,
Rastogi, N., Ahmad, M.K., Mahdi, A.A., Khan, A.R., Thakur, R., Srivastava,
V.K., Mishra, D.P., Fatima, N., Khan, H.J., Waseem, M. (2017). ROS
mediated pro-apoptotic effects of Tinospora
cordifolia on breast cancer cells. Front Biosciences (Elite Ed),
1(9), 89-100.
4. Shivakumar, G.C.,
Sahana, S., Fatima, N., Chaurasia, A. (2016). Comparative Evaluation of
Curcumin Extracts and Lycopene in Leukoplakia. Indian Journal of Dental Education,
9(3), 153-157.
5. Ansari, J.A., Khan,
A.R., Ahmad, M.K., Fatima, N., Rastogi, N., Khan, M.F., Khan, H.J.,
Mahdi, A.A. ( 2016) Phytochemicals, Antioxidant and Antiproliferative Studies
of Some Medicinal Plants from Indian Sub-continent British Journal of
Pharmaceutical Research, 11(6), 1-11.
6. Ansari, J.A.,
Ahmad, M.K., Khan, A.R., Fatima, N., Khan, H.J., Rastogi, N., Mishra,
D.P., Mahdi, A.A. (2016). Antiproliferative and antioxidant activity of Zingiber officinale Roscoe rhizome. Indian Journal of Experimental Biology, 54,
767-773
7. Khan, H.J., Ahmad,
M. K., Khan, A. R., Rastogi, N., Ansari, J. A., Fatima, N., Satyanarayan,
G. N.V., Mahdi, A.A. (2016). GC-MS/MS Based Identification of Bioactive
Principles of Chloroform fraction of Swertia
Chirayatia (Chirata). Oriental. Journal of Chemistry, 32(2),
875-883.
8. Khan, H.J., Ahmad,
M.K., Khan, A.R., Rastogi, N., Mahdi, A.A., Ansari, J.A., Fatima, N., Satyanarayan,
G. N.V. (2016). Identification of Anticancer and Antioxidant phytoconstituents
from chloroform fraction of Solanum nigrum
L. berries using GC-MS/MS analysis. Indian Journal of Experimental Biology.
54, 774-782.
9. Mahdi, A. A.,
Ansari, J. A., Khan, H. J., Fatima, N., Lakshmi, V., Ahmad, M. K.,Khan, A.R., Mahdi,
A.A. (2013). Anticancerous medicinal plants: A review. International Journal of Advances
in Pharmaceutical Research. 4, 1706-22.
10. Ansari, J. A., Ahmad,
M.K., Verma, A.K., Fatima, N., Khan, H.J., Khan, A.R., Mahdi, A. A.
(2015). Microwave assisted determination of 17 minerals and four toxic metals
in traditionally used medicinal plant Zingiber
officinale Roscoe by Inductively Coupled Plasma-Optical Emission
Spectrometer. International Journal of
Advanced Research. 3(4), 879-887.
11. Ishrat, N., Ansari, J. A., Gautam, S., Fatima, N.,
Abid, M., Hassan, F., Mahdi, A. A. (2017). Glucagon like
Peptide-1 Receptor Agonists and its Analogues in the Management of type 2
Diabetes Mellitus Patients: An Overview. Journal of Biological and Chemical Research.
34(2), 610-642.
Book chapter
1.
Fatima,
N., Mahdi, A.A., Ansari, J.A., Ali, Z. Ethnobotany, Phytochemistry and Pharmacology
of Wrightia tinctoria. Biochemistry and Therapeutic Uses of Medicinal
Plants. ISBN: 978-93-5056- Edition: 2017 Published by: Discovery Publishing
House Pvt. Ltd., New Delhi (India).
2.
Fatima, N., Ahmad,
M. K., Ansari, J.A., Ali, Z. Mahdi, A.A. (2017). Therapeutic significance,
phytochemistry and pharmacological activities of Anthocephalus cadamba
(Roxb.) Miq: An overview. Phytochemistry and Pharmacology of Medicinal Herbs.
ISBN: 978-93-85995-46-0. Lenin Media Private Limited, Delhi.
3.
Fatima,
N.,
Ansari, J.A., Mahdi, A.A. (2017). Phytochemicals: Unique aspects as anticancer
agents. Molecular
Biology and Pharmacognosy of Beneficial Plants. ISBN: 978-93-85995-56-9. Lenin
Media Pvt. Limited, Delhi, India.
4.
Fatima,
N.,
Ansari, J.A., Naqvi, T.S., Khan, A.R., Mahdi, A.A. (2017). Heavy Metals,
Incidence, Chemical Risk and Toxicity for Medicinal Plants: A Review. Herbal
Medicine and Modern Drug Discovery. ISBN: 978-93-85995-52-1. Lenin Media Pvt.
Limited, Delhi, India.
5.
Ansari, J.A., Fatima, N., Mahdi, A.A. (2017). Toxicity of Heavy Metals as
Carcinogenic Agent: Mechanism and Prevention by Natural Products. Molecular
Biology and Pharmacognosy of Beneficial Plants. ISBN: 978-93-85995-56-9. Lenin
Media Pvt. Limited, Delhi, India.
6.
Ansari, J.A., Mahdi, A.A., Fatima, N.,
Khan, A.R. (2017). Tinospora cordifolia (Willd.) Miers ex Hook. F. &
Thoms. as a Potent Ethno-Medical Medicinal Plant: A Rational Review. ISBN: 978-
93-5056-866-8, Discovery Publishing House Pvt. Ltd., New Delhi (India).
7.
Hassan F., Ansari, J.A., Ahmad S., Fatima, N.,
Khan, A.R. (2017). The Role of Natural
Products in Diabetes Control. Molecular Biology and Pharmacognosy
of Beneficial Plants. ISBN: 978-93-85995-56-9. Lenin Media Pvt. Limited, Delhi,
India.
8.
Ansari, J.A., Ahmad, M. K., Fatima, N.,
Khan, A.R., Mahdi, A.A.(2017)
Zingiber officinale Roscoe
as a natural gift; An overview of its ethnomedical significance. Phytochemistry
and Pharmacology of Medicinal Herbs. ISBN: 978-93-85995-46-0. Lenin Media
Private Limited, Delhi.
9.
Hassan F., Ansari, J.A., Ahmad S., Fatima, N.,
Khan, A.R. (2017). The Role of Natural Products in the Control of Diabetes. ISBN:
978-93-85995-52-1.Herbal Medicine and Modern Drug Discovery. Published by Lenin
Media Pvt. Limited, Delhi, India.
10.
Ansari, J.A., Fatima, N., Khan, A.R., Abid, M., Naqvi, T.S., Mahdi A.A. (2017).
Naturally occurring secondary metabolites as potent anticancer agents. ISBN:
978-93-85995-52-1.Herbal Medicine and Modern Drug Discovery. Published by Lenin
Media Pvt. Limited, Delhi, India.
11. Ansari,
J.A., Fatima N., Abid, M., Naqvi,
T.S., Mahdi, A.A. (2017). Phytochemical and Pharmacological Review of Musa
paradisiacal L. ISBN: 978-93-85995-52-1. Herbal Medicine and
Modern Drug Discovery. Published by Lenin Media Pvt. Limited, Delhi, India.
CONFERENCES/ MEETINGS/ABSTRACTS
Oral presentations
1.
Fatima, N., Ahmad, M.K.,
Ansari, J.A., Ali, Z., Khan, H.J., Rastogi, N., Khan, A.R., Mahdi, A.A.
Anti-radical and anticancer compounds from non polar fraction of . Wrightia
tinctoria (R.Br.): A bioassay guided approach. International conference on Biotechnological,
advancements in free radical biology and medicine. Integral University,
Lucknow, 23ed-25th January, 2017, P-73.
2.
Fatima, N.,
Ahmad, M. K., Ansari, J. A., Ali, Z., Khan, A. R., Mahdi A. A. Anticancer, Antioxidant
Potential and Profiling of Polyphenolic Compounds of Wrightia tinctoria Roxb. (R.Br.) bark by HPLC-DAD. NRSM
2016.National Research Scholars Meet in Life Sciences, 15-16 December 2016,
Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata
Memorial Centre, Navi Mumbai, Maharashtra. INDIA.
3.
Fatima, N.,
Ansari, J. A., Ahmad, K., Khan, H. J., Khan, A. R., Ali, Z., Mahdi, A. A. Phytochemical
investigation of Wrightia tinctoria
(Roxb.) R.Br. National conference on novel tools and treatment approaches in
health care system, 3rd march 2015, D/o pharmacy, Integral University, Lucknow.
4.
Ansari, J.A., Fatima, N., Ahmad, M.K.,
Khan, A. R., Mahdi, A.A. Isolation and characterization of anticancer compounds
from Tinospora cordifolia. National
symposium on “Changing trends in medical biochemistry in the new millennium”.
4th February, 2017, department of biochemistry, KGMU, Lucknow. P-15.
Poster
presentations
1.
Fatima, N., Ansari, J. A.,
Ahmad, M. K., Khan, A. R., Ali, Z., Abid, M., Mahdi, A. A. Identification of
promising antiproliferative candidates from chloroform fraction of Shweta Kutaja (Wrightia tinctoria). National symposium on “Changing trends in
medical biochemistry in the new millennium”. 4th Febuary, 2017, department of Biochemistry,
KGMU, Lucknow.P-34
2. Khan, H. J., Ahmad,
M. K., Khan, A. R., Waseem, M., Mahdi, A.A., Ansari, J.A., Fatima, N.
Identification of antiproliferative constituents of Swertia chirayata (Chirata)
National symposium on “Changing trends in medical biochemistry in the new
millennium”. 4th Febuary, 2017, department of biochemistry, KGMU, Lucknow.P-24
3.
Fatima, N., Mahdi, A. A.,
Ansari, J. A., Ahmad, M. K., Khan, H. J., Khan, A. R., Ali,Z. Evaluation of in vitro antioxidant activity of Anthocephalus cadamba (Roxb.) Miq bark
fractions. “National symposium on Interfacing chemical biology and drug design”
Amity University, Lucknow, 24th – 25th February, 2015, PP-65.
4. Fatima, N., Ansari, J.A.,
Ahmad, M.K., Khan, H. J., Ali, Z., Mahdi, A. A. In vitro antioxidant activity of Anthocephalus cadamba (Roxb.) Miq and Wrightia tinctoria R. Br. “International conference on recent
advances in research & treatment of human diseases”, Nizam’s Institute of
Medical Sciences, Hyderabad, 9th-11th January 2015, PP-35.
5.
Ansari, J.A., Ahmad, M.K., Fatima N., Khan,
H.J., Hussain, S.R., Abid, M., Verma,A. K., Mahdi, A. A., Analysis of Lead in
water samples from Lucknow city by ICP-OES. 3rd Annual meeting of Indian
Academy of Biomedical Sciences, Department of Biochemistry, JNMC, AMU, Aligarh,
14th-15th December, 2013. PP-57 (Best poster Award).
6.
Ansari, J.A., Khan, H.J., Fatima, N.,
Lakshmi, V., Ahmad, M.K., Khan, A.R., Mahdi, A.A. Preliminary phytochemical
analysis of Solanum nigrum.
International conference on Chemistry: Frontiers and Challenges, AMU, Aligarh,
2nd-3rd March 2013, P-168 ID:481.
7.
Fatima, N., Ali, Z., Ansari,
J.A., Khan, H.J., Ahmad, M.K., Khan, A.R., Mahdi, A.A. Preliminary
phytochemical analysis of traditionally used medicinal plant Anthocephalus cadamba. International
conference on Chemistry: Frontiers and Challenges, AMU, Aligarh, 2nd-3rd March
2013, P-168 ID:480.
8.
Khan, H. J., Ansari, J. A., Fatima, N.,
Ahmad, M. K., Khan, A. R., Mahdi, A. A. Evaluation of phytochemical profile of Swertia chirayata. International
conference on Chemistry: Frontiers and Challenges, AMU, Aligarh, 2nd-3rd March
2013, P-159 ID:453.
9.
Ansari, J.A., Ahmad, M.K., Verma, A.K., Fatima,
N., Khan, H J., Abid, M., Khan, A.R., Mahdi, A.A. A simple Microwave
assisted method for determination of Heavy Metals in Whole
Blood by ICP-OES. National seminar on metal toxicity and oxidative stress,
23rd-24th September, 2014. D/o Biosciences, Jamia Millia Islamia, New Delhi.
10.
Fatima, N., Mahdi, A.A.,
Ansari, J.A., Ahmad, M.K., Khan, H.J., Khan, A.R., Ali,Z. Evaluation of in
vitro antioxidant activity of Anthocephalus
cadamba (roxb.) Miq bark fractions. “National symposium on Interfacing
chemical biology and drug design” Amity University, Lucknow, 24th – 25th
February, 2015, PP-65.
11.
Fatima, N., Ansari J. A.,
Ahmad M. K., Khan H. J., Ali Z., Mahdi A. A. In vitro antioxidant activity of Anthocephalus
cadamba (Roxb.) Miq and Wrightia tinctoria
R. Br. “International Conference on Recent Advances in Research & Treatment
of Human Diseases”, Nizam’s Institute of Medical Sciences, Hyderabad, 9-11th Jan 2015,
PP-35.
Award & Recognition
Award of Women Scientist-A fellowship funded by Department of Science and Technology (SR/WOS-A/CS-109/201), Ministry of Science and Technology, New Delhi, Govt. of India, from 2nd June, 2014 to 1st December, 2017
Specialization
Natural product isolation techniques: Extraction techniques, method development in preparative and semi-preparative HPLC, GC-MS and LC-MS. Isolation techniques including normal phase column chromatography and flash chromatography. · Spectroscopic techniques: FT-NMR, One-dimensional (1H, 13C, Dept), homonuclear two-dimensional (Cosy, Tocsy) and heteronuclear two-dimensional (HSQC, HMBC) NMR, HPLC/UPLC-HRMS, FAB-MS, MALDI-MS, MS/MS and MS. UV-VIS spectroscopy, Interpretation of data and applications in Drug Discovery. · Cell Culture techniques: Mammalian cell culture (suspension and adherent cancer cell lines of different cancer types), Cell based colorimetric and fluorimetric assays. Flow cytometry based assays and CFSE and Propidium iodide based cell sorting. Confocal and fluorescence microscopy. · Trace metal detection techniques: Inductively coupled plasma optical emission spectrometry (ICP-OES), Atomic Absorption Spectroscopy (AAS), Microwave digestive system (MDS) · Statistics and Bioinformatics: ChemDraw, TopSpin 2.1, GraphPad Prism, MS office
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